What concurrent medication should prompt the nurse to withhold cyclobenzaprine?

Cyclobenzaprine is a muscle relaxant commonly prescribed to relieve muscle spasms associated with acute musculoskeletal conditions. It acts centrally in the brain to produce muscle relaxation. When considering concurrent medications, the primary concern is potential interactions that could lead to serious side effects.

Tranylcypromine is an MAO inhibitor, which can interact dangerously with cyclobenzaprine. The combination of these two can lead to serotonin syndrome, a potentially life-threatening condition characterized by symptoms such as confusion, rapid heart rate, and high blood pressure. MAO inhibitors can also enhance the serotonergic effects of certain medications, leading to an increased risk of adverse reactions. Therefore, when a patient is taking tranylcypromine, it is crucial for the nurse to withhold cyclobenzaprine to prevent these serious risks.

The other medications listed, such as ibuprofen, metoprolol, and amoxicillin, have no significant interactions with cyclobenzaprine that would warrant withholding it. Ibuprofen is a nonsteroidal anti-inflammatory drug helpful in managing pain. Metoprolol is a beta-blocker commonly used for hypertension and other heart-related conditions. Amoxicillin is an antibiotic. While these medications may have their